HUMAN PRENATAL CRANIOFACIAL DEVELOPMENT RELATED TO BRAIN-DEVELOPMENT UNDER NORMAL AND PATHOLOGICAL CONDITIONS
HUMAN PRENATAL CRANIOFACIAL DEVELOPMENT RELATED TO BRAIN-DEVELOPMENT UNDER NORMAL AND PATHOLOGICAL CONDITIONS
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DOI：
10.3109/00016359509005963
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发表时间：
1995-06-01
影响因子：
2
通讯作者：
KJAER, I
中科院分区：
文献类型：
--
作者：
KJAER, I
一项调查给出了目前的知识之间的相互关系的面部，颅骨和大脑的发展在人类。首先，分别描述了正常的面部、颅骨（下颌骨、上颌骨、腭骨、颅底、颅膜、牙列）和大脑发育。然后，说明了正常和病理条件下的发育相互关系（唇腭裂，前脑畸形，无脑畸形，羊膜带序列）。详细描述了新的观察结果，并参考了以前发表的文章。面部、颅面骨骼和大脑的发育之间存在着密切的联系。这是通过对腭裂胎儿的新观察和关于全前脑畸形和牙齿发育病因的新理论来说明的。此外，调查的重点是面部和颅底在内分泌发育中的重要性。面部区域和不同发育起源的颅区之间的界限是为了将来阐明涉及颅面区域的综合征背后的病因。
A survey is given of current knowledge of the interrelationship between facial, cranial and brain development in humans. First, normal facial, cranial (mandible, maxilla, palatine bone, cranial base, theca cranii, dentition), and brain development are described separately. Then, developmental interrelationships are illustrated under normal and pathologic conditions (cleft lip and palate, holoprosencephaly, anencephaly, amniotic band sequence). New observations are described in detail, and references are given to previously published articles. A close interconnection exists between the development of the face, the craniofacial skeleton, and the brain. This is illustrated by new observations in cleft palate fetuses and new theories about the etiology of holoprosencephaly and tooth agenesis. The survey focuses, moreover, on the importance of the face and the cranial base in endocrine development. Borderlines between face regions and cranial regions with different developmental origin are set up for future elucidation of the etiology behind syndromes involving the craniofacial regions.