Biochemical differences in children with conduct disorder socialized and undersocialized.
Biochemical differences in children with conduct disorder socialized and undersocialized.
复制标题
患有社会化和社会化程度低的品行障碍儿童的生化差异。
DOI：
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发表时间：
1982
影响因子：
17.7
通讯作者：
E. L. Mitchell
中科院分区：
文献类型：
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作者：
G. Rogeness;J. M. Hernandez;C. A. Macedo;E. L. Mitchell
作者比较了25名品行障碍儿童和20名对照儿童的血浆多巴胺β-羟化酶（DBH）、血小板单胺氧化酶（MAO）、全血5-羟色胺和红细胞儿茶酚O-甲基转移酶（COMT）。他们发现，被诊断为社会化不足的行为障碍儿童的DBH活动明显低于被诊断为社会化行为障碍的儿童和对照组。行为障碍儿童的COMT活性显著高于其他两组。当被诊断为品行障碍和注意力缺陷障碍的儿童与对照组进行比较时，由于两种诊断的混合，没有发现显著的生化差异。
The authors compared plasma dopamine beta-hydroxylase (DBH), platelet monoamine oxidase (MAO), whole blood serotonin, and RBC catechol O-methyltransferase (COMT) in 25 children with conduct disorder and 20 control children. They found that children diagnosed as having conduct disorder undersocialized had significantly lower DBH activity than children diagnosed as having conduct disorder socialized and the control group. The children with conduct disorder socialized had significantly higher COMT activity than the other two groups. When children with a diagnosis of conduct disorder plus a diagnosis of attention deficit disorder were compared with the control group, no significant biochemical differences were found because of the mixing of the two diagnoses.