All fibroblasts are equal, but some are more equal than others.
All fibroblasts are equal, but some are more equal than others.
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所有成纤维细胞都是平等的，但有些成纤维细胞比其他成纤维细胞更平等。
DOI：
10.1038/s41584-024-01097-6
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发表时间：
2024
期刊：
影响因子：
--
通讯作者：
Bolton C
中科院分区：
文献类型：
--
作者：
Bolton C
关节受累的特征模式存在于不同形式的关节炎中。现在的研究表明，滑膜成纤维细胞的表观遗传编程使其对炎性级联的反应多样化，导致关节炎及其治疗反应的这种解剖差异。
Characteristic patterns of joint involvement exist in different forms of arthritis. Research now indicates that epigenetic programming of synovial fibroblasts diversifies their response to inflammatory cascades, leading to this anatomical variation in arthritis and its response to treatment.