Arginine vasotocin immunoreactivity in hypothalamic and extrahypothalamic areas of an amphibian brain.

Arginine vasotocin immunoreactivity in hypothalamic and extrahypothalamic areas of an amphibian brain.
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两栖动物大脑下丘脑和下丘脑外区域的精氨酸催产素免疫反应性。

DOI:
10.1159/000124261
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发表时间:
1986
期刊:
影响因子:
4.1
通讯作者:
Moore,FL
Moore,FL
中科院分区:
医学2区
文献类型:
--
作者:
Zoeller,RT;Moore,FL

文献摘要

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采用显微解剖和放射免疫分析技术研究了雄性粗皮蝾螈脑内精氨酸催产素免疫反应性(irAVT)的分布。在神经内分泌下丘脑-垂体系统中观察到最高水平的irAVT。然而,在下丘脑外区域,如腭、杏仁核、纹状体和丘脑、顶盖和脑干核中也观察到可检测量的irAVT(大于0.40 ng/mg蛋白质)。在嗅球、端脑吻侧或端脑尾侧和间脑的特定区域未检测到irAVT。这些结果表明,在两栖动物中,AVT分布在广泛的脑区,并且irAVT浓度具有区域特异性。
The distribution of arginine vasotocin immunoreactivity (irAVT) was investigated in the brain of male rough-skinned newts (Amphibia:Taricha granulosa)using microdissection and radioimmunoassay techniques. The highest levels of irAVT were observed in the neuroendocrine hypothalamo-hypophysial system. However, detectable quantities of irAVT (greater than 0.40 ng/mg protein) also were observed in extrahypothalamic areas such as pallium, amygdala, striatum and thalamic, tectal and brainstem nuclei. No irAVT was detected in the olfactory bulb, rostral telencephalon, or in specific areas of the caudal telencephalon and diencephalon. These results indicate that, in amphibians, AVT is distributed among a wide range of brain areas and that there is regional specificity in irAVT concentrations.