Stability of Complex Carbohydrate Structures - Biofuels, Foods, Vaccines and Shipwrecks
Stability of Complex Carbohydrate Structures - Biofuels, Foods, Vaccines and Shipwrecks
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复杂碳水化合物结构的稳定性 - 生物燃料、食品、疫苗和沉船
DOI：
10.1039/9781849735643-00036
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发表时间：
2012
期刊：
影响因子：
--
通讯作者：
Grassby T
中科院分区：
文献类型：
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作者：
Grassby T
更详细地研究了与食用 DF 相关的生理效应和健康益处。*“例如，现在已知 NSP 可以降低大量营养素（例如淀粉和脂质）的消化和吸收的速度和程度，”这会导致餐后血糖、血脂和空腹血液胆固醇的减弱。”这种代谢效应与降低患冠心病、中风、肥胖和 2 型糖尿病的风险有关。NSP 被认为改变消化的机制动力学和其他肠道功能是多种多样的，包括粘性溶液的形成、营养物质的封装、消化酶的抑制以及胆汁盐的结合。此外，大肠中微生物发酵 NSP 会产生短链脂肪酸 (SCFA)，目前认为短链脂肪酸对肠道功能和代谢具有重要的积极影响。”本综述将仅关注 NSP 被认为改变消化和餐后代谢时间过程的机制。
have examined the physiological effects and health benefits associated with consumption of DF in more detail.*" For instance, NSP are now known to reduce the rate and extent of digestion and absorption of macronutrients, such as starch and lipid," which leads to attenuation of postprandial glycaemia, lipaemia and also fasting blood cholesterol." Such metabolic effects are linked to a reduced risk of developing coronary heart disease, stroke, obesity and type 2 diabetes mellitus. The mechanisms by which NSP are thought to alter the digestion kinetics and other gut functions are diverse, including formation of viscous solutions, encapsulation of nutrients, inhibition of digestive enzymes, and binding of bile salts. Furthermore, fermentation of NSP by microorganisms in the large intestine results in the production of short chain fatty acids (SCFA), which are now considered to have important positive effects on gut function and metabolism." This review will focus only on the mechanisms of NSP that are considered to alter the time course of digestion and postprandial metabolism.