Phase-contrast and fluorescent X-ray imaging for biomedical researches
Phase-contrast and fluorescent X-ray imaging for biomedical researches
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DOI：
10.1016/j.nima.2005.03.063
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发表时间：
2005-08
影响因子：
1.4
通讯作者：
T. Takeda
中科院分区：
文献类型：
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作者：
T. Takeda
具有相衬和荧光技术的同步加速器x射线成像系统已被开发用于生物医学研究。由于x射线干涉仪相衬x射线成像是一种高度敏感的成像技术，可以区分生物物体内部软组织，因此可以在不使用造影剂的情况下成像详细的形态结构。荧光x射线CT在体积为10 ~ 6ml的情况下，对特定的重原子序数元素，如碘，按picogram的数量级进行检测，从而获得带有标记剂的功能信息。在这里，我描述了最近通过这些成像技术获得的体内和体外实验结果。
Synchrotron X-ray imaging systems with phase-contrast and fluorescent techniques have been developed for biomedical researches. Since phase-contrast X-ray imaging with an X-ray interferometer is a highly sensitive imaging technique to differentiate the inner soft tissue in biological object, detailed morphological structures can be imaged without the use of contrast material. Fluorescent X-ray CT detects specific heavy atomic number elements such as iodine at the order of picogram in a volume of 10−6ml, so the functional information with labeling agents can be obtained. Here, I describe recent in vivo and ex vivo experimental results obtained by these imaging techniques.