Over-time changes in PTSD and depression among children surviving the 1999 Istanbul earthquake
Over-time changes in PTSD and depression among children surviving the 1999 Istanbul earthquake
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DOI：
10.1007/s00787-009-0745-9
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发表时间：
2009-06-01
影响因子：
6.4
通讯作者：
Braun, Kathryn L.
中科院分区：
文献类型：
--
作者：
Eksi, Aysel;Braun, Kathryn L.
以全面的 PTSD 和抑郁症标准对儿童和青少年受害者进行随访，并检查治疗的效果。在土耳其发生 7.4 级地震后一到两个月，对 160 名学生进行了自我报告问卷、精神病学访谈、临床医生管理的创伤后应激障碍量表 (CAPS) 以及抑郁和焦虑量表的检查。基线时，96 名学生被诊断患有创伤后应激障碍 (PTSD)，其中 49 名学生患有抑郁症和焦虑症状。 18-20 个月后，96 名学生中的 74 名被发现并通过精神病访谈和 CAPS 进行了重新评估； 25 人接受过认知行为疗法 (CBT) 和药物疗法，49 人未接受任何治疗。二元逻辑回归用于识别持续性 PTSD 的显着预测因素。输入的变量包括地震前、地震和地震后因素、初次访谈时是否患有共病抑郁症、接受药物治疗以及 CBT 的月数。在随访中，许多人出现了伴有焦虑的 PTSD 症状，但只有 14 名受试者符合 PTSD 的全部标准，其中 4 名学生患有伴有焦虑症状的重度抑郁症。只有一个变量——在地震期间处于严重的人身危险（例如，被困在房子里或瓦砾下）——与随访时出现症状显着相关。无论是否接受治疗，创伤后应激障碍和抑郁症的诊断都大大减少。需要对弹性因素进行更多研究。
To follow-up on child and adolescent victims with full criteria of PTSD and depression, and to examine the impact of treatment.One to two months following a 7.4-magnitude quake in Turkey, 160 students were examined by self-report questionnaire, psychiatric interview, clinician-administered post-traumatic stress disorder scale (CAPS), and depression and anxiety inventories. At baseline, 96 students were diagnosed with PTSD, and 49 had comorbid depression with anxiety symptoms. After 18-20 months, 74 of 96 students were found and reassessed by psychiatric interview and CAPS; 25 had been treated with cognitive-behavioral therapy (CBT) and pharmocotherapy, and 49 did not have any treatment. Binary logistic regression was used to identify significant predictors of persistent PTSD. Variables entered included pre-quake, quake and post-quake factors, having co-morbid depression upon initial interview, receipt of drug therapy, and number of months of CBT.At follow-up, many had symptoms of PTSD with anxiety, but only 14 subjects met the full criteria of PTSD, and four students had major depression with anxiety symptoms. Only one variable-having been in serious personal danger during the quake (e.g., trapped in the house or under rubble)-was significantly associated with being symptomatic at follow-up.Regardless of receipt of treatment, diagnoses of PTSD and depression were much reduced. More research is needed about resiliency factors.