DISEASE DUE TO MYCOBACTERIUM-KANSASII IN THE CZECH-REPUBLIC - 1984-89

DISEASE DUE TO MYCOBACTERIUM-KANSASII IN THE CZECH-REPUBLIC - 1984-89
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DOI:
10.1016/s0962-8479(05)80006-1
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发表时间:
1995-06-01
期刊:
TUBERCLE AND LUNG DISEASE
影响因子:
--
通讯作者:
RICHTROVA, S
RICHTROVA, S
中科院分区:
其他
文献类型:
--
作者:
KAUSTOVA, J;CHMELIK, M;RICHTROVA, S

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背景:捷克共和国北摩拉维亚流行地区。目的:了解甘肃分枝杆菌引起的人类疾病的发病率。随访一些细菌学及临床特征。设计:对堪萨斯分枝杆菌患者进行回顾性分析。结果:1984- 1989年间,从650人的痰、组织和其他标本中分离到堪萨斯分枝杆菌。其中只有471人被认为是这种分枝杆菌的病原体,主要是肺部疾病。这些患者最典型的影像学表现是肺浸润和/或薄壁腔。结论:与往年一样,发病率最高的地区仍然是北摩拉维亚的一个流行地区。随访患者的治疗效果不仅受到抗结核方案的影响,还受到相关疾病的高频率的影响。30天内的痰转归不受有无空腔的影响。作者认为水是传染源。
Setting: Endemic area of North Moravia, Czech Republic.Objective: Evaluate the incidence of human disease due to Mycobacterium kansasii. The follow-up of some bacteriological and clinical features.Design: A retrospective analysis of M. kansasii patients.Results: M. kansasii was isolated from the sputum, tissue and other specimens obtained from 650 persons during the period 1984-89. In only 471 of them was this mycobacterium deemed to be the causative agent, predominantly of lung disease. The most typical radiographic finding in these patients was lung infiltration and/or thin-walled cavity.Conclusion: As in previous years the highest incidence of disease remains in an endemic area of North Moravia. The effects of treatment in followed-up patients were influenced not only by the antituberculosis regimen but also by a high frequency of associated diseases. Sputum conversion within 30 days was not affected by the presence or absence of a cavity. Authors consider water to be the source of infection.