General theoretical approach to the thermodynamic and kinetic properties of cooperative intramolecular transformations of linear biopolymers
General theoretical approach to the thermodynamic and kinetic properties of cooperative intramolecular transformations of linear biopolymers
复制标题
线性生物聚合物分子内协同转化热力学和动力学性质的一般理论方法
作者：
G. Schwarz
A general method to calculate experimentally accessible thermodynamic and kinetic quantities for any type of cooperative transitions is developed. Special attention has been directed to transition curves and mean relaxation times. The procedure is applied to the most general case of nearest‐neighbor cooperativity by using the linear Ising model and the matrix method of evaluation. The various potential types of end effects arid the resulting chain length dependences are discussed in detail. The significance of the theory with respect to the helix‐coil transition of polypeptides as well as to the polyproline I‐II transition is indicated.
