Paternal age as a risk factor for low birthweight
Paternal age as a risk factor for low birthweight
复制标题
DOI：
10.2105/ajph.2005.066324
复制
发表时间：
2006-05-01
影响因子：
12.7
通讯作者：
Teitler, JO
中科院分区：
文献类型：
--
作者：
Reichman, NE;Teitler, JO
目标。我们调查了美国城市人口中父亲的年龄和低出生体重之间的关系。使用基于人口的4621名新生儿的样本，我们使用多元Logistic回归分析来估计父亲年龄与低出生体重之间的关系，并控制母亲年龄、其他人口统计学因素以及孩子的性别。当孩子的性别和母亲的种族/民族、出生地、产次、婚姻状况和医疗保险类型被控制后，十几岁的父亲生下低出生体重婴儿的可能性比20至34岁的父亲低20%，而34岁以上的父亲生下低出生体重婴儿的可能性比20至34岁的父亲高90%。当母亲的年龄也被控制时，这种关联是显著的。在父亲年龄与低出生体重之间的关系上没有发现种族/民族差异。我们发现父亲的年龄是美国城市人口低出生体重的独立危险因素，这表明需要更多地关注父亲对出生结果的影响，以及城市环境和个人风险因素对健康的交互影响。
Objectives. We examined associations between paternal age and low birthweight in the US urban population.Methods. Using a population-based sample of 4621 births, we used multiple logistic regression analysis to estimate associations between paternal age and low birthweight, controlling for maternal age, other demographic factors, and the child's gender.Results. When the child's gender and the mother's race/ethnicity, birthplace, parity, marital status, and health insurance type were controlled, teenaged fathers were 20% less likely and fathers older than 34 years were 90% more likely than fathers aged 20 to 34 years to have low-birthweight babies. The associations were significant when maternal age was also controlled. No racial/ethnic differences in associations between paternal age and low birthweight were found.Conclusions. We identified paternal age as an independent risk factor for low birthweight in the US urban population, suggesting that more attention needs to be paid to paternal influences on birth outcomes and to the interactive effects of urban environments and individual risk factors on health.