The Influence of Age and Sex on Cervical Spinal Alignment Among Volunteers Aged Over 50
The Influence of Age and Sex on Cervical Spinal Alignment Among Volunteers Aged Over 50
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DOI：
10.1097/brs.0000000000001071
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发表时间：
2015-10-01
期刊：
影响因子：
3
通讯作者：
Matsuyama, Yukihiro
中科院分区：
文献类型：
--
作者：
Oe, Shin;Togawa, Daisuke;Matsuyama, Yukihiro
研究设计. 50岁以上志愿者的大型队列研究目的。探讨年龄和性别对50岁以上人群颈椎矢状位的影响。很少有大规模的研究描述了年龄和性别对50岁以上志愿者颈椎对线的正常值。研究队列包括656名年龄在50至89岁之间的志愿者。骨盆倾斜度、骶骨倾斜度、骨盆倾斜度、腰椎前凸、骨盆倾斜度、腰椎前凸、胸椎后凸、11 °倾斜度（T1 S）、颈椎前凸（CL）、C7矢状垂直轴（C7 SVA）、C2 C7 SVA和T1 s CL均使用站立位拍摄的全脊柱和骨盆X线片进行测量。采用FuroQOL（EQ-5D）标准化健康结局量表和奥斯韦斯特里残疾指数评估健康相关生活质量。36例受试者的年龄为50 - 59岁，174例受试者的年龄为60 - 69岁，311例受试者的年龄为70 - 79岁，135例受试者的年龄为80 - 89岁。男性每10年的平均T1 S分别为32度、31度、33度和36度，女性分别为28度、29度、32度和37度。男性C2 C7 SVA平均值分别为25、28、34和35 mm，女性分别为20、21、22和28 HMI。在其他病例中，与FQ-5D相关的C2-C7 SVA 40 MI或以上，-F1 S 40或以上，和-11 S CL 20度或以上明显更差。在所有年龄组中，男性的C2-C7 SVA显著更大，特别是在C2-C7 SVA为40 ri或更大的那些中[男性，69%（82/118）vs.女性，33%（36/118）]。男性的颈椎曲度参数明显差于女性。C2 C7 SVA、5和T1 S CL对FQ-5D有负面影响。这些结果有助于解释老年男性中脊髓型颈椎病的患病率较高。
Study Design. Large cohort study of volunteers aged over 50.Objective. To investigate influence of age and sex on cervical sagittal alignment among volunteers aged over 50.Summary of Background Data. Few large-scale studies have described normative values in cervical spine alignment regarding age and sex among volunteers aged over 50.Methods. The study cohort included 656 volunteers aged 50 to 89 years. Pelvic tilt, sacral slope, pelvic incidence, lumbar lordosis, pelvic incidence lumbar lordosis, thoracic kyphosis, 11 slope (T1S), cervical lordosis (CL), C7 sagittal vertical axis (C7 SVA), C2 C7 SVA, and T1s CL were measured using whole spine and pelvic radiographs taken in the standing position. Health related quality of life was assessed using the FuroQOL (EQ-5D) standardized instrument for measurement of health outcome and Oswestry Disability Index.Results. There were 36 subjects aged 50 to 59 years, 174 aged 60 to 69 years, 311 aged 70 to 79 years, and 135 aged 80 to 89 years. Average T1 S for each decade was 32 degrees, 31 degrees, 33 degrees, and 36 degrees for males, and 28 degrees, 29 degrees, 32 degrees, and 37 degrees for females, respectively. Average C2 C7 SVA was 25, 28, 34, and 35 mm for males, and 20, 21, 22, and 28 HMI for females, respectively. C2-C7 SVA 40 MI or more, -F1S 40 or more, and -11 S CL 20 degrees or more pertaining to FQ-5D were significantly worse in other cases.Conclusion. C2-C7 SVA was significantly greater in males among all age groups, particularly among those with C2-C7 SVA of 40 ri or more [males, 69% (82/118) vs. females, 33% (36/118)1. Sagittal parameters of cervical spine were significantly worse in males than females. C2 C7 SVA, 5, and T1S CL negatively influenced FQ-5D. These results help to explain the greater prevalence of cervical spondylotic myelopathy among elderly males.