Production of piperonal, vanillin, and p-anisaldehyde via solventless supported iodobenzene diacetate oxidation of isosafrol, isoeugenol, and anethol under microwave irradiation
Production of piperonal, vanillin, and p-anisaldehyde via solventless supported iodobenzene diacetate oxidation of isosafrol, isoeugenol, and anethol under microwave irradiation
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DOI：
10.1021/op060117t
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发表时间：
2006-09-15
影响因子：
3.4
通讯作者：
Antunes, O. A. C.
中科院分区：
文献类型：
--
作者：
Alvarez, Heiddy Marquez;Barbosa, Dayse P.;Antunes, O. A. C.
介绍了一种以活性烯烃和负载型二乙酸碘苯为原料，在微波辐射下合成羰基化合物的新实验方法。通过改变反应条件，可以以合理到优异的产率和选择性生成相应的醛。该方法简单、干净、重现性好，反应时间短。使用异黄樟醇、异丁香酚和茴香酚可以分别生产胡椒醛、香草醛和对苯甲醛。
A novel experimental procedure to obtain carbonyl compounds under microwave irradiation from activated olefins and supported iodobenzene diacetate is described. By varying the reaction conditions it is possible to generate the corresponding aldehydes in reasonable-to-excellent yields and selectivities. The methodology is simple, clean, and reproducible and presents short reaction times. Using isosafrol, isoeugenol, and anethol it was possible to produce piperonal, vanillin and p-anisaldehyde, respectively.