[Age changes in pupillary light reflex. A demonstration by means of a pupillometer].
[Age changes in pupillary light reflex. A demonstration by means of a pupillometer].
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[瞳孔对光反射的年龄变化。
DOI：
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发表时间：
1989
期刊：
影响因子：
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通讯作者：
S. Ishikawa
中科院分区：
文献类型：
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作者：
S. Hasegawa;S. Ishikawa
研制了一种新型的固体显像管双目红外视频瞳孔仪（C-2515, Hamamatsu Photonics）。各种瞳孔参数由内置的计算机系统即时分析。该设备还可以将数据存储在软盘上。研究了持续时间为250 msec（强度为3000 troland）的光刺激引起的光反射。对光反射的几个参数进行了分析。这些是：瞳孔面积，光刺激面积的变化，收缩率，潜伏期和63%振幅时的扩张时间。共研究了160名受试者（320只眼睛）。年龄从5岁到84岁不等，被试被安排在相应的10岁年龄组（如0-9岁、10-19岁、20-29岁、30-39岁等）。每组10名男性和10名女性。研究了双眼的光反射。瞳孔面积随年龄增长而减小，呈负相关。50岁以上女性的瞳孔面积缩小幅度更大，可能是由于激素的影响。20岁时潜伏期最短。10岁以下和60岁以上的受试者潜伏期较其他年龄组明显延长。计算了收缩速度与扩张速度之比，发现两者呈负相关。这可能表明存在与年龄和瞳孔动态相关的交感神经影响。结果表明，通过这种新的瞳孔图对光反射的检查，可以准确地表达出年龄对瞳孔的影响。
A new binocular infrared video-pupillograph (C-2515, Hamamatsu Photonics) with a solid state vidicon tube was developed. Various pupil parameters were instantaneously analyzed by a built-in computer system. The equipment also enabled storage of the data on diskettes. A light reflex, induced by a photic stimulus with a duration of 250 msec (intensity: 3,000 troland) was studied. Several parameters of the light reflex were analyzed. These were: pupil area, change in the area of light stimulus, rate of constriction, latency time, and dilatation time at 63% of the amplitude. A total of 160 subjects (320 eyes) was studied. The ages ranged from 5 to 84 years, and subjects were placed in appropriate ten-year age groups (e.g., 0-9 years, 10-19, 20-29, 30-39, etc.). Ten males and 10 females were included in each group. The light reflex was studied in both eyes. The pupil area reduced as the age advanced, with negative correlation. The pupil area in females over 50 years showed a steeper reduction in size, possibly due to hormonal influences. The latency time at 20 years old was the shortest. In subjects below 10 and over 60 years, the latency time was significantly prolonged when compared with the other age groups. The ratio of the velocity of constriction against the velocity of dilatation was calculated and a negative correlation was seen. This may indicate that there are sympathetic influences related to aging and pupil dynamics. The results revealed that an examination of the light reflex by this new pupillography expressed the precise influence of aging on the pupil.