Understanding and Preventing the Global Increase of Inflammatory Bowel Disease
Understanding and Preventing the Global Increase of Inflammatory Bowel Disease
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DOI：
10.1053/j.gastro.2016.10.020
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发表时间：
2017-02-01
期刊：
影响因子：
29.4
通讯作者：
Ng, Siew C.
中科院分区：
文献类型：
--
作者：
Kaplan, Gilaad G.;Ng, Siew C.
炎症性肠病(IBD)是工业化社会的当代病症。IBD在西方国家的患病率继续稳步上升，新兴工业化国家的发病率迅速上升。IBD的全球传播似乎与饮食和环境的西化有关，这会影响肠道微生物群，并增加遗传易感个体患IBD的风险。增加对这些事件的认识对于延缓IBD的进展是很重要的。我们提出了一项长期计划，以开发干预措施，减缓或阻止全球IBD发病率的增加。
The inflammatory bowel diseases (IBDs) are contemporary conditions of industrialized societies. The prevalence of IBD continues to increase steadily in Western countries, and newly industrialized countries have a rapidly increasing incidence. The global spread of IBD appears to associate with Westernization of diets and environments, which affects the intestinal microbiome and increases the risk of IBD in genetically susceptible individuals. It is important to increase our understanding of these events to slow progression of IBD. We present a long-term plan to develop interventions that slow or stop the global increase in the incidence of IBD.