Analysis of the Genetic Effects of Three Genes Involved in de novo Purine Biosynthesis on IMP Content in Baier Chickens
Analysis of the Genetic Effects of Three Genes Involved in de novo Purine Biosynthesis on IMP Content in Baier Chickens
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发表时间：
2010
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通讯作者：
Shu;Jing-ting;Zhang;Xue-yu;Han;Wei;Chen;Guo-hong;Poultry;Yangzhou
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作者：
Shu;Jing-ting;Zhang;Xue-yu;Han;Wei;Chen;Guo-hong;Poultry;Yangzhou
GPAT、AIRC和purH基因参与了嘌呤的新生生物合成，它们都对鸡肌磷酸肌苷（IMP）含量有显著影响。本试验旨在研究GPAT、AIRC和purH基因对较大种群贝尔鸡肌肉IMP含量的影响；分析了单基因型效应和组合基因型效应。结果进一步支持GPAT、AIRC和purH基因对肌肉IMP含量的影响；它们可能是候选基因座或与影响肌肉IMP含量的主要基因有关。组合基因型效应显著高于单一基因型效应，当组合基因位点较多时，组合基因型效应更大。我们初步认为，组合基因型优于单基因型作为肉质性状的潜在分子标记。
GPAT,AIRC and purH genes are involved in the de novo purine biosynthesis,and they all had significant effects on muscle inosine monophosphate(IMP) content in chickens.This study was designed to investigate the effects of GPAT,AIRC and purH genes on muscle IMP content in a relatively large population of Baier chickens;single genotype effects as well as the combined genotype effects were analyzed.The results further support that GPAT,AIRC and purH genes had effects on muscle IMP content;they might be candidate loci or linked to major genes affecting muscle IMP content.The combined genotypic effects were significantly higher than those of the single genotypes and were even larger when more gene loci were combined.We tentatively conclude that combined genotypes are superior to single genotypes as potential molecular markers for meat quality traits in chicken.