Chapter 1:Electrical Modifications of Biomaterials' Surfaces: Beyond Hydrophobicity and Hydrophilicity
Chapter 1:Electrical Modifications of Biomaterials' Surfaces: Beyond Hydrophobicity and Hydrophilicity
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第一章：生物材料表面的电改性：超越疏水性和亲水性
DOI：
10.1039/9781849733366-00003
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发表时间：
2011
影响因子：
6.6
通讯作者：
A. Gandhi
中科院分区：
文献类型：
--
作者：
S. Tofail;A. Gandhi
本章讨论了生物材料电改性的各种方法，沿着讨论了它们的优缺点。据报道，在生物材料中赋予电荷的电修饰具有有益效果，特别是在骨生成中。据报道，负极性生物材料表面的钙化率和细胞活动率较高。由于表面的疏水性/亲水性，这种一般观察结果不能完全一致，因为目前的理论并没有表明表面的极性对润湿行为有任何影响。需要更多的基础研究，以获得一个正确的理解电修改的报告选择性刺激矿化。
Various methods of the electrical modification of biomaterials are discussed in this Chapter, along with their advantages and disadvantages. Electrical modifications to impart electrical charge in biomaterials have been reported to have beneficial effect, in particular in osteogenesis. Higher rates of calcifications and cellular activities have been reported on negatively polarized Biomaterials' surfaces. This general observation cannot be reconciled purely due to the hydrophobicity/hydrophilicity of the surface, as the current theory does not suggest any influence of polarity of the surface on wetting behaviour. More fundamental studies are required to obtain a proper understanding of electrical modification on the reported selectivity in the stimulation of mineralization.