FIBER ORIENTATION IN CANINE LEFT VENTRICLE DURING DIASTOLE AND SYSTOLE
FIBER ORIENTATION IN CANINE LEFT VENTRICLE DURING DIASTOLE AND SYSTOLE
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DOI：
10.1161/01.res.24.3.339
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发表时间：
1969-01-01
影响因子：
20.1
通讯作者：
SONNENBLICK, EH
中科院分区：
文献类型：
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作者：
STREETER, DD;SPOTNITZ, HM;SONNENBLICK, EH
研究了左心室心肌壁的纤维取向。从18只犬心脏中获得标本，这些心脏在收缩期、舒张期和扩张期快速原位固定。纤维取向确定跨游离壁在八个网站从T形标本通过测量与光学显微镜在连续石蜡切片。结果表明：（1）壁具有从内表面处的约60°（从周向方向）到外表面上的约-60°变化的纤维角度的良好有序分布。相对于壁厚的角度变化最大发生在两个表面（心内膜和心外膜）。(2)纤维角度没有显着变化，在过渡期从收缩期，尽管增加了28%的壁厚（乳头肌根部区域除外）。(3)位于圆周方向（0±22.5°）的纤维角与纵向方向（67.5至90°和-67.5至-90°）的纤维角的扇区中的纤维的比例约为10：1。该比率向左心室底部增加，向左心室顶部减小。(4)收缩期心脏侧壁的所有纤维角在基底附近通过壁增加约7°，在心尖附近增加约19°，相对于收缩期的对应物，表明收缩期间左心室弯曲或扭转。
Fiber orientation across the left ventricular myocardial wall has been studied. Specimens were obtained from 18 dog hearts rapidly fixed in situ in systole, in diastole, and in dilated diastole. Fiber orientation was determined across the free wall at eight sites from a T-shaped specimen by measurements with light microscopy in serial paraffin sections. Results indicate: (1) The wall has a well-ordered distribution of fiber angles varying from about 60° (from the circumferential direction) at the inner surface to about -60° on the outer surface. The greatest change in angle with respect to wall thickness occurs at the two surfaces (endocardial and epicardial). (2) Fiber angles did not change significantly during the transition from diastole to systole, despite a 28% increase in wall thickness (except in the papillary muscle root region). (3) The proportion of fibers lying in the sector of fiber angles oriented circumferentially (0±22.5°) to those oriented longitudinally (67.5 to 90° and -67.5 to -90°) is approximately 10:1. This ratio increases toward the base and diminishes toward the apex of the left ventricle. (4) All fiber angles in the lateral wall of hearts in systole increased through the wall by approximately 7° near the base and 19° near the apex relative to their counterparts in diastole, indicating bending or torsion of the left ventricle during contraction.