Severe Thrombocytopenia after Zika Virus Infection, Guadeloupe, 2016.

Severe Thrombocytopenia after Zika Virus Infection, Guadeloupe, 2016.
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DOI:
10.3201/eid2304.161967
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发表时间:
2017-04
影响因子:
11.8
通讯作者:
Hoen B
Hoen B
中科院分区:
医学2区
文献类型:
--
作者:
Boyer Chammard T;Schepers K;Breurec S;Messiaen T;Destrem AL;Mahevas M;Soulillou A;Janaud L;Curlier E;Herrmann-Storck C;Hoen B

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寨卡病毒感染期间或之后的严重血小板减少症很少报告。我们报告7例严重血小板减少症和出血的体征和症状在瓜德罗普感染这种病毒后。临床病程和实验室检查结果强烈提示寨卡病毒感染与免疫介导的血小板减少症之间存在因果关系。
Severe thrombocytopenia during or after the course of Zika virus infection has been rarely reported. We report 7 cases of severe thrombocytopenia and hemorrhagic signs and symptoms in Guadeloupe after infection with this virus. Clinical course and laboratory findings strongly suggest a causal link between Zika virus infection and immune-mediated thrombocytopenia.