Facile and efficient fabrication of photoresponsive microgels via thiol-Michael addition.
Facile and efficient fabrication of photoresponsive microgels via thiol-Michael addition.
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DOI：
10.1002/marc.201200439
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发表时间：
2012-11
影响因子：
4.6
通讯作者：
Huijuan Zhang;Y. Xin;Q. Yan;Lilin Zhou;Liao Peng;Jinying Yuan
中科院分区：
文献类型：
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作者：
Huijuan Zhang;Y. Xin;Q. Yan;Lilin Zhou;Liao Peng;Jinying Yuan
将非共价组装策略与共价交联方法相结合，设计了一种光敏微凝胶。端基功能化的偶氮苯聚乙二醇[(聚乙二醇偶氮)(2)]与丙烯酸酯修饰的β-CD(β-CD-MAA)通过主客体相互作用形成光响应性包合物。通过Michael加成点击反应，将上述光响应性络合物通过硫醇功能化的聚乙二醇缩乙二硫醇(PEG-Dithiol)进行交联。用透射电子显微镜、紫外可见光谱和核磁共振氢谱研究了微凝胶的光可逆性。表征结果表明，通过交替的UV-Vis照射可以实现微凝胶的可逆尺寸变化，且具有良好的重复性。
A photoresponsive microgel is designed by the combination of a noncovalent assembly strategy with a covalent cross-linking method. End-functionalized poly(ethylene glycol) with azobenzene [(PEG-(Azo)(2))] was mixed with acrylate-modified β-CD (β-CD-MAA) to form photoresponsive inclusion complex through host-guest interaction. The above photoresponsive complex was cross-linked by thiol-functionalized PEG (PEG-dithiol) via Michael addition click reaction. The photoreversibility of resulted microgel was studied by TEM, UV-Vis spectroscopy, and (1)H NMR measurements. The characterization results indicated that the reversible size changes of the microgel could be achieved by alternative UV-Vis irradiations with good repeatability.