Brain cytokines and neuropsychiatric disorders.
Brain cytokines and neuropsychiatric disorders.
复制标题
DOI：
10.1097/01.jcp.0000148026.86483.4f
复制
发表时间：
2004-12
影响因子：
2.9
通讯作者：
T. Theoharides;Craig C. Weinkauf;P. Conti
中科院分区：
文献类型：
--
作者：
T. Theoharides;Craig C. Weinkauf;P. Conti
所有骨髓来源的多能干细胞的分化。细胞因子也具有炎症和调节作用。急性应激诱导白细胞运输并增强免疫反应。事实上，急性应激可增加肥大细胞依赖性血清白细胞介素-6（IL-6），其涉及选择性释放而不脱颗粒。升高的血清IL-6是全身性肥大细胞增多症患者的特征，在这些患者中，应激可促使癫痫发作。IL-6的过度产生也参与了苯巴比妥过敏。
differentiation of all bone marrow–derived pluripotent stem cells. Cytokines also have inflammatory and regulatory actions. Acute stress induces leukocyte trafficking and augments immune responses. In fact, acute stress can increase mast cell–dependent serum interleukin-6 (IL-6) that involves selective release without degranulation. Elevated serum IL-6 is characteristic in systemic mastocytosis patients in whom stress can precipitate seizures. IL-6 overproduction was also involved in phenobarbital hypersensitivity.