Variation in vector competence for dengue 2 virus among 24 collections of Aedes aegypti from Mexico and the United States
Variation in vector competence for dengue 2 virus among 24 collections of Aedes aegypti from Mexico and the United States
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DOI：
10.4269/ajtmh.2002.67.85
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发表时间：
2002-07-01
影响因子：
3.3
通讯作者：
Beaty, BJ
中科院分区：
文献类型：
--
作者：
Bennett, KE;Olson, KE;Beaty, BJ
从墨西哥和美国收集的24只埃及伊蚊用2型登革热病毒JAM1409 （DEN-2 JAM1409）进行了口攻。种群的媒介能力（VC）为24% ~ 83%。来自尤卡坦半岛的蚊子种群比来自墨西哥其他地区的蚊子表现出更高的VC。测定每个种群中蚊子是否存在中肠感染屏障（MIB）和中肠逃逸屏障（MEB）。在收集的蚊子中，表现出MIB的蚊子比例为14%至59%，表现出MEB的蚊子比例为4%至43%。通过回归分析可知，MIB和MEB并不完全独立。中肠感染率呈剂量依赖性。
Aedes aegypti from 24 collections in Mexico and the United States were challenged orally with dengue 2 virus JAM1409 (DEN-2 JAM1409). The vector competence (VC) of the populations ranged from 24% to 83%. Mosquito populations from the Yucatan exhibited greater VC than those from other areas of Mexico. The presence or absence of a midgut infection barrier (MIB) and a midgut escape barrier (MEB) was determined for mosquitoes in each population. The percentage of mosquitoes exhibiting an MIB ranged from 14% to 59%, and those exhibiting an MEB ranged from 4% to 43% in the collections. The MIB and MEB were not completely independent as determined by regression analysis. Midgut infection rates were dose dependent.