BIOSYNTHESIS OF PENICILLINS .7. OXYACETIC AND MERCAPTOACETIC ACIDS

BIOSYNTHESIS OF PENICILLINS .7. OXYACETIC AND MERCAPTOACETIC ACIDS
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DOI:
10.1021/ja01189a003
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发表时间:
1948-01-01
影响因子:
15
通讯作者:
JONES, RG
JONES, RG
中科院分区:
化学1区
文献类型:
--
作者:
SOPER, QF;WHITEHEAD, CW;JONES, RG

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随着对取代乙酸用于生物合成Peni-Cillins的研究的继续,已经制备和测试了一大系列ROCH2COOH和RSCH2COOH类型的氧基乙酸乙酯和RSCH2COOH乙酸乙酯及其某些衍生物。测试3·4的方法以及所产生的一些青霉素6的分离和特性已经在前面介绍过了。
A continuation of the studies on the use of sub-stituted acetic acids for the biosynthesis of peni-cillins has led to the preparation and testing of a large series of oxy-and mercaptoacetic acids of the types ROCH2COOH and RSCH2COOH and cer-tain of their derivatives. The methods oftest-ing3· 4 and the isolation and characterization of some of the resulting penicillins6 have been covered previously.