Dermatofibrosarcoma protuberans with COL1A1 (exon 18) –PDGFB (exon 2) fusion transcript
Dermatofibrosarcoma protuberans with COL1A1 (exon 18) –PDGFB (exon 2) fusion transcript
复制标题
隆突性皮肤纤维肉瘤与 COL1A1（外显子 18）-PDGFB（外显子 2）融合转录本
DOI：
10.1046/j.1365-2133.2003.05367.x
复制
发表时间：
2003
影响因子：
10.3
通讯作者：
K. Tamaki
中科院分区：
文献类型：
--
作者：
H. Saeki;H. Ohmatsu;T. Hoashi;N. Asano;T. Idezuki;Y. Kawabata;A. Asahina;K. Kikuchi;K. Tamaki
摘要 背景隆突性皮肤纤维肉瘤(DFSP)中已发现I型胶原蛋白1( I型α1，COL1A1)基因与血小板衍生生长因子B链(PDGFB)基因融合。COL1A1基因的多个外显子参与了与PDGFB基因外显子2的融合。
Summary Background Fusion of the collagen type I α 1 (COL1A1) gene with the platelet‐derived growth factor B‐chain (PDGFB) gene has been described in dermatofibrosarcoma protuberans (DFSP). Various exons of the COL1A1 gene have been shown to be involved in the fusion with exon 2 of the PDGFB gene.