Assessing the potential of metal oxide semiconducting gas sensors for illicit drug detection markers
Assessing the potential of metal oxide semiconducting gas sensors for illicit drug detection markers
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DOI：
10.1039/c4ta00357h
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发表时间：
2014-01-01
影响因子：
11.9
通讯作者：
Parkin, I. P.
中科院分区：
文献类型：
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作者：
Hernandez, P. Tarttelin;Naik, A. J. T.;Parkin, I. P.
以预防贩毒为重点的港口安全需要廉价和便携式系统对集装箱进行现场分析，以尽量减少过境延误。这里探讨了金属氧化物半导体用于非法药物检测的潜力。设计了由WO 3和SnO 2油墨组成的六传感器阵列。将沸石H-Y和H-ZSM-5结合以引入传感器响应的变化。对传感器进行了测试，以丙酮、乙醇和甲苯作为其用于非法药物制造的替代物，并测试了氨和二氧化氮作为含氨基和硝基化合物的第一个模型，因为它们在药物和前体分子的结构框架中很普遍。沸石材料的加入大大提高了传感器的灵敏度和选择性。发现混合的传感材料对气体特别敏感。支持向量机被应用到数据集作为分类工具，准确地根据气体类型的数据进行分类。传感阵列成功地靶向和辨别测试的药物标记物。这可能是未来基于MOS技术的电子鼻检测非法药物的关键。
Port security with a focus on drug trafficking prevention requires inexpensive and portable systems for onsite analysis of containers in order to minimise transit delays. The potential of metal oxide semiconductors for illicit drug detection is explored here. A six-sensor array consisting of WO3 and SnO2 inks was devised. Zeolites H-Y and H-ZSM-5 were incorporated to introduce variations in sensor response. Sensors were tested against acetone, ethanol and toluene as proxies for their use in illicit drug manufacture and against ammonia and nitrogen dioxide as first models of amino-and nitro-containing compounds, given their prevalence in the structural framework of drugs and precursor molecules. Sensor sensitivity and selectivity were greatly enhanced by inclusion of zeolite materials. Admixed sensing materials were found to be particularly sensitive to the gases. Support vector machines were applied to the dataset as classification tools that accurately classified the data according to gas type. The sensing array was successful in targeting and discerning between the tested drug markers. This could be key for illicit drug detection with electronic noses based on MOS technology in the future.