Prevention of maternal and congenital cytomegalovirus infection.
Prevention of maternal and congenital cytomegalovirus infection.
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DOI：
10.1097/grf.0b013e3182510b7b
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发表时间：
2012-06-01
影响因子：
1.5
通讯作者：
Pass, Robert F
中科院分区：
文献类型：
--
作者：
Johnson, Julie;Anderson, Brenna;Pass, Robert F
先天性巨细胞病毒(CMV)感染是导致听力障碍、智力低下和脑性瘫痪的重要原因。怀孕期间的主要感染源是幼儿和亲密接触者。预防母体和先天性巨细胞病毒感染有赖于向妇女提供有关感染源的咨询和可能预防感染的卫生措施。目前没有足够的证据支持将抗病毒治疗或被动免疫用于孕妇暴露后预防或作为旨在预防胎儿感染的孕产妇治疗。针对CMV的疫苗正在开发中，但还需要数年时间才能获得许可。
Congenital cytomegalovirus (CMV) infection is an important cause of hearing impairment, mental retardation, and cerebral palsy. Principal sources of infection during pregnancy are young children and intimate contacts. Prevention of maternal and congenital CMV infection depends on counseling women regarding the sources of infection and hygienic measures that might prevent infection. There is currently insufficient evidence to support use of antiviral treatment or passive immunization for postexposure prophylaxis of pregnant women or as a maternal treatment aimed at preventing fetal infection. Vaccines for CMV are under development but it will be a number of years before one is licensed.