Highly stereoselective [3 + 2] annulations by cyclopropanation of vinyl ethers with rhodium(II)-stabilized vinylcarbenoids followed by a formally forbidden 1,3-sigmatropic rearrangement
Highly stereoselective [3 + 2] annulations by cyclopropanation of vinyl ethers with rhodium(II)-stabilized vinylcarbenoids followed by a formally forbidden 1,3-sigmatropic rearrangement
复制标题
通过乙烯基醚与铑 (II) 稳定的乙烯基类胡萝卜素的环丙烷化，然后进行正式禁止的 1,3-σ 重排，实现高度立体选择性 [3 2] 成环
DOI：
10.1021/jo00037a041
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发表时间：
1992
影响因子：
3.6
通讯作者：
Baihua Hu
中科院分区：
文献类型：
--
作者：
H. Davies;Baihua Hu
A highly stereoselective 3 + 2 annulation has been developed by cyclopropanation of vinyl ethers with rhodium(II)-stabilized vinylcarbenoids to generate vinylcyclopropanes followed by a Et 2 AlCl-catalyzed 1,3-sigmatropic rearrangement. The success of this methodolgy rests on the remarkably stereoselectivity that is exhibited in both the cyclopropanation step and also the Et 2 AlCl-catalyzed vinylcyclopropane rearrangement
