CELL LINEAGE RELATIONSHIPS IN IMAGINAL WING DISC OF DROSOPHILA-MELANOGASTER
CELL LINEAGE RELATIONSHIPS IN IMAGINAL WING DISC OF DROSOPHILA-MELANOGASTER
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DOI：
10.1016/0012-1606(70)90160-0
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发表时间：
1970-01-01
影响因子：
2.7
通讯作者：
BRYANT, PJ
中科院分区：
文献类型：
--
作者：
BRYANT, PJ
本文对果蝇成虫翅盘的衍生物--翅和中背层的细胞谱系进行了描述。该系统进行了分析，使用体细胞交换，诱导X射线在特定的发展阶段。克隆相关的细胞占据了翅膀的纵向条纹，这被解释为细胞分裂是在发育中的圆盘中定向的。克隆相关的细胞占据不规则形状的区域中的肠系膜，但一些非随机性是可检测的。这些数据表明，在胚胎中，推测翅盘细胞不确定为上翅，下翅，和mesonotum之间。然而，在幼虫中，这三种结构的原基由椎间盘内单独的增殖细胞群代表。这些细胞群具有不同的细胞分裂速率和模式。这些数据被用来估计细胞数量在光盘的三个部分在不同的发展阶段。看来，增长率的部分翼盘是恒定的整个幼虫的发展。结果进行了讨论有关的问题，在成虫盘的形态发生。
An account is given of the patterns of cell lineage in the wing and mesonotum, the derivatives of the imaginal wing disc ofDrosophila melanogaster. The system was analyzed using somatic crossing over, induced by X-rays at specific stages of development. Clonally related cells occupy longitudinal stripes in the wing, and this is interpreted to mean that cell divisions are oriented in the developing disc. Clonally related cells occupy irregularly shaped areas in the mesonotum, but some nonrandomness is detectable. The data indicate that, in the embryo, presumptive wing disc cells are not determined as between upper wing, lower wing, and mesonotum. In the larva, however, the anlagen of these three structures are represented by separate populations of proliferating cells within the disc. These groups of cells have distinct rates and patterns of cell division. The data were used to estimate cell numbers in the three parts of the disc at various stages of development. It appears that the growth rates of the parts of the wing disc are constant throughout larval development. The results are discussed in relation to problems of morphogenesis in imaginal discs.