Pre-erythrocytic Stage of Plasmodium Falciparum
Pre-erythrocytic Stage of Plasmodium Falciparum
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恶性疟原虫红细胞前阶段
DOI：
10.1136/bmj.2.4635.1006
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发表时间：
1949
影响因子：
--
通讯作者：
P. Garnham
中科院分区：
文献类型：
--
作者：
H. Shortt;N. Fairley;G. Covell;P. G. Shute;P. Garnham
提到了用胆碱或其前体补充酒精饮料和糖精充气水(“软饮料”)的建议所涉及的问题。当然，我们的发现并不一定适用于人类受试者中的酒精中毒。如果事实证明是这样的话，越来越明显的是，习惯性摄入大量酒精或糖的人缺乏足够量的促脂剂以及其他饮食必需品。人类受试者中与酒精中毒相关的典型肝损害(脂肪改变和纤维化)，我们在介绍中第一次描述，可能被证明是由于缺乏趋脂剂。
Problems connected with the proposal to supplement alcoholic beverages and saccharine aerated water (" soft drinks ") with choline or its precursors are mentioned. Our findings are, of course, not necessarily applicable to alcoholism in human subjects. If they should prove to be so, it is increasingly obvious that individuals who habitually consume large amounts of alcohol or sugar lack adequate amounts of the lipotropic agents as well as of other dietary essentials. The classical hepatic lesions (fatty changes and fibrosis) associated with alcoholism in human subjects, the first descriptions of which are rfientioned in our introduction, may prove to be due specifically to a lack of the lipotropic agents.