Influence of hydrostatic pressure gradients on regulation of plasma volume after exercise.
Influence of hydrostatic pressure gradients on regulation of plasma volume after exercise.
复制标题
静水压力梯度对运动后血浆容量调节的影响。
DOI:
10.1152/jappl.1998.85.2.667
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发表时间:
1998
期刊:
影响因子:
--
通讯作者:
Haskell,A
中科院分区:
文献类型:
--
作者:
Mack,GW;Yang,R;Hargens,AR;Nagashima,K;Haskell,A
The impact of posture on the immediate recovery of intravascular fluid and protein after intense exercise was determined in 14 volunteers. Forces which govern fluid and protein movement in muscle interstitial fluid pressure (PISF), interstitial colloid osmotic pressure (COPi), and plasma colloid osmotic pressure (COPp) were measured before and after exercise in the supine or upright position. During exercise, plasma volume (PV) decreased by 5.7 ± 0.7 and 7.0 ± 0.5 ml/kg body weight in the supine and upright posture, respectively. During recovery, PV returned to its baseline value within 30 min regardless of posture. PV fell below this level by 60 and 120 min in the supine and upright posture, respectively (P< 0.05). Maintenance of PV in the upright position was associated with a decrease in systolic blood pressure, an increase in COPp(from 25 ± 1 to 27 ± 1 mmHg;P< 0.05), and an increase in PISF(from 5 ± 1 to 6 ± 2 mmHg), whereas COPiwas unchanged. Increased PISFindicates that the hydrostatic pressure gradient favors fluid movement into the vascular space. However, retention of the recaptured fluid in the plasma is promoted only in the upright posture because of increased COPp.