ArrayExpress--a public repository for microarray gene expression data at the EBI.
ArrayExpress--a public repository for microarray gene expression data at the EBI.
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DOI：
10.1093/nar/gki056
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发表时间：
2005-01-01
影响因子：
14.9
通讯作者：
Brazma A
中科院分区：
文献类型：
--
作者：
Parkinson H;Sarkans U;Shojatalab M;Abeygunawardena N;Contrino S;Coulson R;Farne A;Lara GG;Holloway E;Kapushesky M;Lilja P;Mukherjee G;Oezcimen A;Rayner T;Rocca-Serra P;Sharma A;Sansone S;Brazma A
ArrayExpress是一个微阵列数据的公共知识库，它支持微阵列实验最小信息量（MIAME）要求，并存储有详细注释的原始数据和标准化数据。截至2004年11月，ArrayExpress包含来自约12000次杂交的数据，涵盖35个物种。数据可以在线提交，也可以从本地数据库或实验室信息管理系统（LIMS）以标准格式直接提交，并且为审稿人和作者提供对预发表数据的密码保护访问。数据可以通过登录号检索，也可以通过各种参数（如物种、作者和阵列平台）查询。对于加载到ArrayExpress数据仓库中不断增加的精选数据子集，提供了一种通过基因和样本特性查询实验的工具。可以使用集成数据分析工具Expression Profiler对数据进行可视化和分析。ArrayExpress可在http://www.ebi.ac.uk/arrayexpress获取。
ArrayExpress is a public repository for microarray data that supports the MIAME (Minimum Informa-tion About a Microarray Experiment) requirements and stores well-annotated raw and normalized data. As of November 2004, ArrayExpress contains data from ∼12 000 hybridizations covering 35 species. Data can be submitted online or directly from local databases or LIMS in a standard format, and password-protected access to prepublication data is provided for reviewers and authors. The data can be retrieved by accession number or queried by vari-ous parameters such as species, author and array platform. A facility to query experiments by gene and sample properties is provided for a growing subset of curated data that is loaded in to the ArrayExpress data warehouse. Data can be visualized and analysed using Expression Profiler, the integrated data analysis tool. ArrayExpress is available at http://www.ebi.ac.uk/arrayexpress.