Rapid and quantitative analysis of pesticides in fruits by QuEChERS pretreatment and low-temperature plasma desorption/ionization orbitrap mass spectrometry
Rapid and quantitative analysis of pesticides in fruits by QuEChERS pretreatment and low-temperature plasma desorption/ionization orbitrap mass spectrometry
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DOI：
10.1039/c4ay00103f
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发表时间：
2014-08-07
影响因子：
3.1
通讯作者：
Engelhard, Carsten
中科院分区：
文献类型：
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作者：
Albert, Anastasia;Kramer, Andrea;Engelhard, Carsten
环境解吸/电离高分辨率质谱法（ADI-HR-MS）是分析复杂样品的一种强有力的方法。近年来，直接分析实时质谱（DART）和低温等离子体探针质谱（LTP）在直接农药残留定性筛选和液体提取物中农药定量分析方面显示出了潜力。本研究建立了一种用于水果提取物中农药残留定量分析的LTP-HR-MS方法，并根据欧盟农药法规对其进行了评价。该研究特别关注了德国过去报道的经常超过法定最大残留水平的不同水果母体中的农药（即醋氨虫、环虫腈、苯甲醚和氟菌腈；见2009年德国联邦消费者保护和食品安全办公室的报告）。通过优化方法，采用LTP-Orbitrap-MS对加标和未加标水果QuEChERS提取物中的农药进行了准确的质量测定(
Ambient desorption/ionization high-resolution mass spectrometry (ADI-HR-MS) is a powerful method for the analysis of complex samples. Recently, direct analysis in real time (DART) MS and low-temperature plasma probe (LTP) MS demonstrated potential in direct qualitative pesticide residue screening and quantitative analysis of pesticides in liquid extracts. In the present study, a LTP-HR-MS method for quantitative pesticide residue analysis in fruit extracts was developed and evaluated with respect to the European Union (EU) legislation on pesticides. In particular, this study focused on pesticides in different fruit matrices that were reported to often exceed legal maximum residue levels (MRLs) in Germany in the past (namely acetamiprid, cyprodinil, fenhexamid, and fludioxonil; see report on of the German Federal Office of Consumer Protection and Food Safety in 2009). After method optimization, pesticides in spiked and unspiked fruit QuEChERS extracts were identified successfully by LTP-Orbitrap-MS via accurate mass measurements (