Fiducial-based targeting accuracy for external-beam radiotherapy
Fiducial-based targeting accuracy for external-beam radiotherapy
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DOI：
10.1118/1.1448823
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发表时间：
2002-03-01
期刊：
影响因子：
3.8
通讯作者：
Murphy, MJ
中科院分区：
文献类型：
--
作者：
Murphy, MJ
分析了基于基准的放射治疗光束对准的精度。该研究考虑了确定目标位置的三种基本计算方法——三个基准的精确封闭解，四个或更多基准的奇异值分解解，以及任意数量基准的迭代解——并评估了它们的准确性、鲁棒性和效率。特别要注意的是由软组织中基准位置的可变性引起的不准确性。在几乎所有的测试用例中，我们都发现这三种解方法在正确实施的情况下，对目标位置产生相同的结果，但是必须修改奇异值分解方法以区分旋转和反射。当需要精确测量目标位置的旋转时，4个基准比3个基准的结果要好得多，而超过5个基准的结果几乎没有进一步的改善。(C) 2002年美国医学物理学家协会。
The accuracy of fiducial-based alignment of external radiotherapy beams is analyzed. The study considers three basic computational methods to determine the target position-the exact closed-form solution for three fiducials, the solution via singular value decomposition for four or more fiducials, and the iterative solution for any number of fiducials-and assesses their accuracy, robustness, and efficiency. Particular attention is paid to inaccuracies arising from the variability of fiducial positions in soft tissue. In nearly every test case it is found that all three solution methods, when properly implemented, yield the same result for the target position, but that the method of singular value decomposition must be modified to distinguish rotations from reflections. When an accurate measure of the rotation of the target site is needed, four fiducials give much better results than three, while more than five fiducials gain little further improvement. (C) 2002 American Association of Physicists in Medicine.