Top-down control of MEG alpha-band activity in children performing Categorical N-Back Task
Top-down control of MEG alpha-band activity in children performing Categorical N-Back Task
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DOI：
10.1016/j.neuropsychologia.2010.08.006
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发表时间：
2010-10-01
期刊：
影响因子：
2.6
通讯作者：
Hamalainen, Matti S.
中科院分区：
文献类型：
--
作者：
Ciesielski, Kristina T.;Ahlfors, Seppo P.;Hamalainen, Matti S.
自上而下的认知控制与成人的前额叶-顶叶网络有关 在儿童中，自上而下控制的大脑机制很少被研究 我们通过在视觉工作记忆任务的预期目标检测和反应后阶段期间监测阿尔法波段振荡活动（8-13 Hz）的事件相关去同步（ERD）和事件相关同步（ERS）来检查自上而下认知控制的发育差异 使用脑磁图（MEG）记录大脑还获得了执行分类 N-Back 任务 (CNBT) 的健康 10 岁儿童和年轻人的振荡活动，评估额叶网络的神经心理学测量结果成人在 CNBT 的预期阶段表现出 ERD 的调节，在反应后阶段的 ERS 儿童仅表现出一些 ERD 的预期调节，但在反应后阶段没有 ERS，其中 α 波段保持在不同步状态。神经影像学结果表明，10 岁儿童的前额叶-顶叶网络尚未完全发育，并且由于儿童在 CNBT 上的表现与成人相同，但表现出不同的 ERD/ERS 模式，我们认为儿童可能使用不同的自上而下的认知策略，因此具有不同的发育适应性神经网络 (C) 2010 Elsevier Ltd 保留所有权利
Top-down cognitive control has been associated in adults with the prefrontal-parietal network In children the brain mechanisms of top-down control have rarely been studied We examined developmental differences in top-down cognitive control by monitoring event-related desynchronization (ERD) and event-related synchronization (ERS) of alpha-band oscillatory activity (8-13 Hz) during anticipation target detection and post-response stages of a visual working memory task Magnetoencephalography (MEG) was used to record brain oscillatory activity from healthy 10-year-old children and young adults performing the Categorical N-Back Task (CNBT) Neuropsychological measures assessing frontal lobe networks were also acquired Whereas adults showed a modulation of the ERD at the anticipatory stages of CNBT and ERS at the post-response stage children displayed only some anticipatory modulation of ERD but no ERS at the post-response stage with alpha-band remaining at a desynchronized state Since neuropsychological and prior neuroimaging findings indicate that the prefrontal-parietal networks are not fully developed in 10-year olds and since the children performed as well as the adults on CNBT and yet displayed different patterns of ERD/ERS we suggest that children may be using different top-down cognitive strategies and hence different developmentally apt neuronal networks (C) 2010 Elsevier Ltd All rights reserved