Generation of (amino)(boryloxy)carbenes from carbamoylboranes and their coupling reaction with aldehydes
Generation of (amino)(boryloxy)carbenes from carbamoylboranes and their coupling reaction with aldehydes
复制标题
由氨基甲酰硼烷生成(氨基)(硼酰氧基)卡宾及其与醛的偶联反应
DOI：
10.1039/d1cc06377d
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发表时间：
2022
影响因子：
4.9
通讯作者：
Kusama Hiroyuki
中科院分区：
文献类型：
--
作者：
Ishida Kento;Kusama Hiroyuki
氨基硼烷在加热条件下可与多种醛反应，产率高。一项DFT研究支持该机制，该机制涉及热生成（氨基）（硼氧基）碳中间体。据我们所知，这是关于氨基硼烷生成（氨基）（硼氧基）碳中间体及其在碳-碳成键反应中的应用的第一篇报道。
Carbamoylboranes were found to react with various aldehydes under heating conditions to give α-hydroxycarboxamides in good yields. A DFT study supports the mechanism, which involves thermally generated (amino)(boryloxy)carbene intermediates. To our knowledge, this is the first report on the generation of (amino)(boryloxy)carbene intermediates from carbamoylboranes and its application to carbon–carbon bond-forming reactions.