PROTINFO: secondary and tertiary protein structure prediction
PROTINFO: secondary and tertiary protein structure prediction
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DOI：
10.1093/nar/gkg541
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发表时间：
2003-07-01
影响因子：
14.9
通讯作者：
Samudrala, R
中科院分区：
文献类型：
--
作者：
Hung, LH;Samudrala, R
关于蛋白质序列的二级和三级结构的信息可以极大地帮助生物学家产生和测试假设，以及设计实验。PROTINFO服务器允许用户提交蛋白质序列，并请求基于作者开发的比较建模、折叠生成和从头方法预测三维（三级）结构。此外，用户可以提交NMR化学位移数据，并请求基于使用神经网络将化学位移与二级结构预测联合收割机相结合的蛋白质二级结构分配。该服务器位于http://protinfo.compbio.washington.edu。
Information about the secondary and tertiary structure of a protein sequence can greatly assist biologists in the generation and testing of hypotheses, as well as design of experiments. The PROTINFO server enables users to submit a protein sequence and request a prediction of the three-dimensional (tertiary) structure based on comparative modeling, fold generation and de novo methods developed by the authors. In addition, users can submit NMR chemical shift data and request protein secondary structure assignment that is based on using neural networks to combine the chemical shifts with secondary structure predictions. The server is available at http://protinfo.compbio.washington.edu.