Prevalence of Diabetic Retinopathy in India Sankara Nethralaya Diabetic Retinopathy Epidemiology and Molecular Genetics Study Report 2
Prevalence of Diabetic Retinopathy in India Sankara Nethralaya Diabetic Retinopathy Epidemiology and Molecular Genetics Study Report 2
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DOI：
10.1016/j.ophtha.2008.09.010
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发表时间：
2009-02-01
期刊：
影响因子：
13.7
通讯作者：
Sharma, Tarun
中科院分区：
文献类型：
--
作者：
Raman, Rajiv;Rani, Padmaja Kumari;Sharma, Tarun
目的：这项研究的目的是估计糖尿病视网膜病变的患病率在城市印度人口年龄超过40 years.Design：一个人口为基础的横断面study.Participants：五千九百九十九个科目居住在印度钦奈，enumerated.Methods：一个多阶段随机抽样，基于社会经济学标准，如下。确定的糖尿病受试者（基于世界卫生组织标准）在基地医院接受详细检查。所有患者均采用45 °、4视野立体数码摄影术拍摄眼底照片。糖尿病视网膜病变的诊断是基于早期治疗糖尿病视网膜病变研究量表的Klein分类。主要结果测量：这些包括年龄和性别调整的糖尿病和糖尿病视网膜病变患病率，以及患病率与基于病史的危险因素的相关性。在钦奈城市人群中，经年龄和性别调整的糖尿病患病率为28.2%。（95%可信区间[CI]，27.0-29.3），一般人群中糖尿病视网膜病变的患病率为3.5%（95% CI，3.49-3.54）。糖尿病人群中糖尿病视网膜病变的患病率为18.0%（95%CI，16.0-20.1）。与糖尿病视网膜病变风险增加显著相关的基于病史的变量包括性别（男性风险更高;比值比（OR），1.41; 95% CI，1.04-1.91）;使用胰岛素（OR，3.52; 95%CI，2.05-6.02）;糖尿病病程较长（>15年; OR，6.43; 95%CI，3.18-12.90）;以及已知患有糖尿病的受试者（OR，2.98; 95%CI，1.72-5.17）。社会经济地位的差异并不影响发生的diabetic retinopathy.Conclusions：糖尿病视网膜病变的患病率为18%，在印度的糖尿病城市人口。糖尿病的持续时间是糖尿病视网膜病变的最强预测因子。财务披露：作者对本文中讨论的任何材料没有专有或商业利益。Ophthalmology 2009;116：311-318（C）2009，美国眼科学会。
Objective: The aim of the study was to estimate the prevalence of diabetic retinopathy in an urban Indian population older than 40 years.Design: A population-based cross-sectional study.Participants: Five thousand nine hundred ninety-nine subjects residing in Chennai, India, were enumerated.Methods: A multistage random sampling, based on socioeconomic criteria, was followed. Identified subjects with diabetes mellitus (based on the World Health Organization criteria) underwent detailed examination at the base hospital. The fundi of all patients were photographed using 45 degrees, 4-field stereoscopic digital photography. The diagnosis of diabetic retinopathy was based on Klein's classification of the Early Treatment Diabetic Retinopathy Study scale.Main Outcome Measures: These included age- and gender-adjusted prevalence of diabetes and diabetic retinopathy, and correlation of prevalence with history-based risk factors.Results: The age- and gender-adjusted prevalence rate of diabetes in an urban Chennai population was 28.2% (95% confidence interval [CI), 27.0-29.3), and the prevalence of diabetic retinopathy in general population was 3.5% (95% CI, 3.49-3.54). The prevalence of diabetic retinopathy in the population with diabetes mellitus was 18.0% (95% CI, 16.0-20.1). History-based variables that were significantly associated with increased risk of diabetic retinopathy included gender (men at greater risk; odds ratio (OR], 1.41; 95% CI, 1.04-1.91); use of insulin (OR, 3.52; 95% CI, 2.05-6.02); longer duration of diabetes (>15 years; OR, 6.43; 95% CI, 3.18-12.90); and subjects with known diabetes mellitus (OR, 2.98; 95% CI, 1.72-5.17). Differences in the socioeconomic status did riot influence the occurrence of diabetic retinopathy.Conclusions: The prevalence of diabetic retinopathy was 18% in an urban population with diabetes mellitus in India. The duration of diabetes is the strongest predictor for diabetic retinopathy.Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article. Ophthalmology 2009;116:311-318 (C) 2009 by the American Academy of Ophthalmology.