Three-Dimensional Innervation Zone Imaging from Multi-Channel Surface EMG Recordings.
Three-Dimensional Innervation Zone Imaging from Multi-Channel Surface EMG Recordings.
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DOI：
10.1142/s0129065715500240
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发表时间：
2015-09
影响因子：
8
通讯作者：
Zhang Y
中科院分区：
文献类型：
--
作者：
Liu Y;Ning Y;Li S;Zhou P;Rymer WZ;Zhang Y
准确识别痉挛肌神经支配区 (IZ) 的位置，以指导肉毒杆菌毒素 (BTX) 注射以获得最佳临床结果，这一需求尚未得到满足。通过结合生物电源成像和表面肌电图 (EMG) 分解方法，开发了一种新颖的 3 维 IZ 成像 (3DIZI) 方法，对目标肌肉中 IZ 的 3D 分布进行成像。从运动单位动作电位 (MUAP) 的双极图中识别出的运动单位 (MU) 的表面 IZ 位置被用作 3DIZI 方法中的先验知识，以提高其成像精度。 3DIZI 方法的性能首先通过一系列设计的计算机模拟进行优化和评估，然后使用肌内 EMG 数据以及同时记录的来自两个受试者二头肌的 128 通道表面 EMG 数据进行验证。模拟和实验验证结果都证明了 3DIZI 方法在根据高密度表面 EMG 记录准确重建 IZ 分布和二头肌内肌活动动态传播方面具有高性能。
There is an unmet need to accurately identify the locations of innervation zones (IZs) of spastic muscles, so as to guide botulinum toxin (BTX) injections for the best clinical outcome. A novel 3-dimensional IZ imaging (3DIZI) approach was developed by combining the bioelectrical source imaging and surface electromyogram (EMG) decomposition methods to image the 3D distribution of IZs in the target muscles. Surface IZ locations of motor units (MUs), identified from the bipolar map of their motor unit action potentials (MUAPs) were employed as a prior knowledge in the 3DIZI approach to improve its imaging accuracy. The performance of the 3DIZI approach was first optimized and evaluated via a series of designed computer simulations, and then validated with the intramuscular EMG data, together with simultaneously recorded 128-channel surface EMG data from the biceps of two subjects. Both simulation and experimental validation results demonstrate the high performance of the 3DIZI approach in accurately reconstructing the distributions of IZs and the dynamic propagation of internal muscle activities in the biceps from high-density surface EMG recordings.