Comparison of Pandemic (H1N1) 2009 and Seasonal Influenza, Western Australia, 2009

Comparison of Pandemic (H1N1) 2009 and Seasonal Influenza, Western Australia, 2009
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DOI:
10.3201/eid1609.100076
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发表时间:
2010-09-01
影响因子:
11.8
通讯作者:
Effler, Paul
Effler, Paul
中科院分区:
医学2区
文献类型:
--
作者:
Carcione, Dale;Giele, Carolien;Effler, Paul

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我们比较了2009年流感季节在西澳大利亚州确诊的2009年大流行性(H1N1)流感和季节性流感。从3,178份合格报告中,选择了984名大流行性流感患者和356名季节性流感患者;分别采访了871名(88.5%)和288名(80.9%)。两组患者报告的11种症状中位值为6种;两组之间报告任何给定症状的比例差异= 1种基础疾病,仅糖尿病与2009年流感大流行(H1N1)相关(比值比[OR] 1.9,95%置信区间[Cl] 1.1-3.5)。共有129名(14.8%)2009年H1N1大流行患者和36名(12.5%)季节性流感患者住院治疗(p = 0.22)。在控制年龄后,我们发现患者住院与2009年大流行(H1N1)流感相关(OR 1.5; 95% CI 1.1-2.1)。同期大流行和季节性流感感染在患者症状、危险因素和住院比例方面基本相似。
We compared confirmed pandemic (H1N1) 2009 influenza and seasonal influenza diagnosed in Western Australia during the 2009 influenza season. From 3,178 eligible reports, 984 pandemic and 356 seasonal influenza patients were selected; 871 (88.5%) and 288 (80.9%) were interviewed, respectively. Patients in both groups reported a median of 6 of 11 symptoms; the difference between groups in the proportion reporting any given symptom was = 1 underlying condition, and only diabetes was associated with pandemic (H1N1) 2009 influenza (odds ratio [OR] 1.9, 95% confidence interval [Cl] 1.1-3.5). A total of 129 (14.8%) persons with pandemic (H1N1) 2009 and 36 (12.5%) persons with seasonal influenza were hospitalized (p = 0.22). After controlling for age, we found that patient hospitalization was associated with pandemic (H1N1) 2009 influenza (OR 1.5; 95% Cl 1.1-2.1). Contemporaneous pandemic and seasonal influenza infections were substantially similar in terms of patients' symptoms, risk factors, and proportion hospitalized.