A single fragment of a malaria merozoite surface protein remains on the parasite during red cell invasion and is the target of invasion-inhibiting antibodies.
A single fragment of a malaria merozoite surface protein remains on the parasite during red cell invasion and is the target of invasion-inhibiting antibodies.
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DOI：
10.1084/jem.172.1.379
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发表时间：
1990-07-01
期刊：
影响因子：
--
通讯作者：
Holder AA
中科院分区：
文献类型：
--
作者：
Blackman MJ;Heidrich HG;Donachie S;McBride JS;Holder AA
源自前体的多肽复合物存在于疟疾裂殖子的表面上。在红细胞入侵期间，该复合物中只有一小部分保留在寄生虫表面并被带入新感染的红细胞中。针对该片段的抗体将阻断入侵。
A complex of polypeptides derived from a precursor is present on the surface of the malaria merozoite. During erythrocyte invasion only a small fragment from this complex is retained on the parasite surface and carried into the newly infected red cell. Antibodies to this fragment will interrupt invasion.