Double-blind comparison of desipramine and placebo in withdrawal from cocaine dependence.

Double-blind comparison of desipramine and placebo in withdrawal from cocaine dependence.
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地昔帕明和安慰剂在戒除可卡因依赖方面的双盲比较。

DOI:
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发表时间:
1984
期刊:
影响因子:
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通讯作者:
Tarver Al
Tarver Al
中科院分区:
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文献类型:
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作者:
Tennant Fs;Tarver Al

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地昔帕明与安慰剂在双盲条件下进行了比较,以确定它是否是有效的可卡因依赖戒断治疗。11例受试者接受地昔帕明,11例接受安慰剂。两组在自我报告的有效性、治疗保留率、停止使用可卡因或抑制戒断评分方面没有显著的统计学差异。虽然地昔帕明似乎并不比安慰剂更有效地戒断可卡因使用或抑制戒断评分,它可能是有用的,在长期治疗这种情况。
: Desipramine was compared with a placebo under double-blind conditions to determine if it is effective treatment for withdrawal from cocaine dependence. Eleven (11) subjects received desipramine and 11 received placebo. There was no significant statistical difference between groups in self-report on effectiveness; retention in treatment; cessation of cocaine use; or suppression of withdrawal scores. Although desipramine appears to be no more effective than placebo in withdrawal from cocaine use or suppression of withdrawal scores, it may be useful in the long-term treatment of this condition.