PREVALENCE OF MITRAL-VALVE PROLAPSE IN PRESUMABLY HEALTHY-YOUNG MEN
PREVALENCE OF MITRAL-VALVE PROLAPSE IN PRESUMABLY HEALTHY-YOUNG MEN
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DOI：
10.1161/01.cir.59.4.619
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发表时间：
1979-01-01
期刊：
影响因子：
37.8
通讯作者：
LESSER, LE
中科院分区：
文献类型：
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作者：
DARSEE, JR;MIKOLICH, JR;LESSER, LE
通过对107名男性医生和医学生进行仰卧位、坐位和站立位心脏听诊的研究，确定了二尖瓣脱垂(MVP)在假定健康的年轻男性中的患病率。101例受试者在吸入亚硝酸戊酯前后进行仰卧位静息超声心动图检查。在101例受试者中，11例听诊有异常表现：4例有孤立的滴答声，7例有滴答声和收缩晚期杂音。101名受试者的独立听诊和超声心动图数据的相关性显示，所有7名有滴答声和杂音的受试者都有脱垂的超声心动图证据。在90名听诊正常的受试者和4名单独发出滴答声的受试者中，没有一人有异常的超声心动图。7例MVP患者均有胸骨异常，但仅1例有症状。健康年轻男性中MVP的患病率与报道的健康年轻女性中6-10%的患病率相似。
The prevalance of mitral valve prolapse (MVP) in presumably healthy young men was determined by studying 107 male physicians and medical students with cardiac auscultation in the supine, sitting and standing positions. Echocardiograms were performed at rest in the supine position before and after amyl nitrite inhalation and were obtained in 101 subjects. Of the 101 subjects, 11 had abnormal findings on auscultation: 4 had an isolated click and 7 had a click and late systolic murmur. Correlation of the independent auscultatory and echocardiographic data in the 101 subjects showed that all 7 subjects with a click and a murmur had echocardiographic evidence of prolapse. None of the 90 subjects with normal auscultation or the 4 with an isolated click had an abnormal echocardiogram. All 7 subjects with MVP had thoracic skeletal abnormalities, but only 1 was symptomatic. The prevalence of MVP in healthy young males in similar to the reported 6-10% prevalence in healthy young females.