Knowledge Translation Strategy to Reduce the Use of Potentially Inappropriate Medications in Hospitalized Elderly Adults
Knowledge Translation Strategy to Reduce the Use of Potentially Inappropriate Medications in Hospitalized Elderly Adults
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DOI：
10.1111/jgs.14322
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发表时间：
2016-12-01
影响因子：
6.3
通讯作者：
Brazeau, Serge
中科院分区：
文献类型：
--
作者：
Cossette, Benoit;Bergeron, Josee;Brazeau, Serge
目的：评估知识转化（KT）策略在减少住院老年人潜在不适当用药（PIM）使用中的效果。设计：对中断时间序列进行分段回归分析。单位：教学医院。参与者：2013/14年度出院的75岁及以上个体（平均年龄83.3岁，54.5%为女性）。干预措施：KT战略包括分发教育材料、老年病专家介绍、基于计算机警报系统警报的药剂师-医生干预措施以及全面的老年评估。测量：PIM使用率（使用至少一种PIM的患者天数/年龄≥75岁的患者住院天数）。结果：对8,622例入院的14,071例患者，共分析了145,061患者日。在28,776（19.8%）患者-天中开具了一种或多种pim处方；75 ~ 84岁人群的发病率（24.0%）高于85岁及以上人群（14.4%）
OBJECTIVES: To evaluate the effect of a knowledge translation (KT) strategy to reduce potentially inappropriate medication (PIM) use in hospitalized elderly adults.DESIGN: Segmented regression analysis of an interrupted time series.SETTING: Teaching hospital.PARTICIPANTS: Individuals aged 75 and older discharged from the hospital in 2013/14 (mean age 83.3, 54.5% female).INTERVENTION: The KT strategy comprises the distribution of educational materials, presentations by geriatricians, pharmacist-physician interventions based on alerts from a computerized alert system, and comprehensive geriatric assessments.MEASUREMENTS: Rate of PIM use (number of patientdays with use of at least one PIM/number of patient-days of hospitalization for individuals aged >= 75).RESULTS: For 8,622 patients with 14,071 admissions, a total of 145,061 patient-days were analyzed. One or more PIMs were prescribed on 28,776 (19.8%) patient-days; a higher rate was found for individuals aged 75 to 84 (24.0%) than for those aged 85 and older (14.4%) (P