Spatial Frequency Domain Imaging (SFDI) of clinical burns: A case report.
Spatial Frequency Domain Imaging (SFDI) of clinical burns: A case report.
复制标题
临床烧伤的空间频域成像 (SFDI)：病例报告。
DOI：
10.1016/j.burnso.2020.02.004
复制
发表时间：
2020
期刊：
影响因子：
--
通讯作者：
Durkin,AnthonyJ
中科院分区：
文献类型：
--
作者：
Ponticorvo,Adrien;Rowland,Rebecca;Baldado,Melissa;Kennedy,GordonT;Hosking,Anna-Marie;Burmeister,DavidM;Christy,RobertJ;Bernal,NicoleP;Durkin,AnthonyJ
虽然临床医生的视觉评估是烧伤严重程度评估的护理标准，但处于不同发展阶段的新技术正试图通过量化烧伤严重程度来增加这种做法的客观性。评估准确性通常在烧伤进展后提高，但正确识别浅表部分和深部分烧伤的早期评估有可能导致更及时的治疗和更短的恢复时间。迄今为止，空间频域成像（SFDI）仅用于烧伤的动物模型，但已显示出在早期时间点准确分类烧伤的潜力。在这里，我们研究了SFDI评估临床患者烧伤严重程度的潜力。我们还利用激光散斑成像（LSI），这是一种FDA批准的非侵入性成像技术，通常用于测量血液灌注，以评估临床患者的烧伤。我们提出了一个病例系列的两名患者，都与不同严重程度的部分厚度烧伤。临床医生通常难以仅根据视觉外观对部分厚度烧伤进行分类。SFDI和LSI都进行了约24和72小时后，他们各自的烧伤事件的每一个病人。每种技术都能够提供空间分辨信息，从而提高每次烧伤的评估准确性。这是SFDI在动物模型中成功应用后首次应用于临床烧伤患者，并强调了SFDI作为及时分类烧伤严重程度的可行工具的潜力。
While visual assessment by a clinician is the standard of care for burn severity evaluations, new technologies at various stages of development are attempting to add objectivity to this practice by quantifying burn severity. Assessment accuracy generally improves after the burn injury has progressed, but early assessments that correctly identify superficial partial and deep partial burns have the potential to lead to more prompt treatments and shorter recovery times. To date, Spatial Frequency Domain Imaging (SFDI) has only been used in animal models of burns, but has shown the potential to categorize burns accurately at earlier time points. Here we examine the potential for SFDI to assess burn severity in clinical patients. We also utilize Laser Speckle Imaging (LSI), an FDA cleared non-invasive imaging technology that typically measures blood perfusion in order to evaluate burns in clinical patients. We present a case series of two patients, both with partial thickness burns of varying severity. Partial thickness burns are often difficult for clinicians to categorize based on visual appearance alone. SFDI and LSI were both performed on each patient at approximately 24 and 72 h after their respective burn incidents. Each technique was able to render spatially resolved information that enabled improved assessment accuracy for each burn. This represents the first publication of SFDI applied to clinical burn patients after being successfully utilized in animal models, and highlights the potential for SFDI as a feasible tool for the timely categorization of burn severity.