Actin filament assembly by bacterial factors VopL/F: Which end is up?
Actin filament assembly by bacterial factors VopL/F: Which end is up?
复制标题
细菌因素导致的肌动蛋白丝组装 VopL/F：哪一端朝上？
DOI：
10.1083/jcb.201702165
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发表时间：
2017
期刊：
影响因子：
--
通讯作者：
Quinlan,MargotE
中科院分区：
文献类型：
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作者：
Vizcarra,ChristinaL;Quinlan,MargotE
已经提出了细菌蛋白VopL/F对肌动蛋白丝成核的竞争模型。在这个问题上，Burke et al.（2017. 201608104）使用直接观察来证明VopL/F结合肌动蛋白丝的倒刺和尖端，但仅从尖端成核新丝。
Competing models have been proposed for actin filament nucleation by the bacterial proteins VopL/F. In this issue, Burke et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201608104) use direct observation to demonstrate that VopL/F bind the barbed and pointed ends of actin filaments but only nucleate new filaments from the pointed end.