The prevalence, impairment, impact, and burden of premenstrual dysphoric disorder (PMS/PMDD)

The prevalence, impairment, impact, and burden of premenstrual dysphoric disorder (PMS/PMDD)
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DOI:
10.1016/s0306-4530(03)00098-2
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发表时间:
2003-08-01
影响因子:
3.7
通讯作者:
Kahn, LS
Kahn, LS
中科院分区:
医学2区
文献类型:
--
作者:
Halbreich, U;Borenstein, J;Kahn, LS

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目前,据估计,3-8%的育龄妇女符合经前焦虑症(PMDD)的严格标准。对已发表报告的评估表明,临床相关的经前焦虑症的患病率可能更高。13-18%的育龄妇女可能有经前焦虑症状,严重到足以引起损害和痛苦,尽管症状的数量可能不符合PMDD列表中5种症状的任意计数。PMDD的损害和生活质量降低与心境恶劣障碍相似,并不比重度抑郁症低多少。尽管如此,PMS/PMDD在大量已发表的流行病学研究以及疾病负担评估中仍然认识不足。研究表明,经前综合症/经前抑郁症的负担以及因这种重复周期性疾病而损失的残疾调整生命年(DALY)与公认的主要疾病相同。对这种疾病及其影响的适当认识应该会导致更多患有经前综合症/经前抑郁症的女性接受治疗。有效的治疗是可行的。它们应减少个人的痛苦和对家庭、社会和经济的影响。(C)2003爱思唯尔科技有限公司版权所有。
Currently it is estimated that 3-8% of women of reproductive age meet strict criteria for premenstrual dysphoric disorder (PMDD). Assessment of published reports demonstrate that the prevalence of clinically relevant dysphoric premenstrual disorder is probably higher. 13-18% of women of reproductive age may have premenstrual dysphoric symptoms severe enough to induce impairment and distress, though the number of symptoms may not meet the arbitrary count of 5 symptoms on the PMDD list.The impairment and lowered quality of life for PMDD is similar to that of dysthymic disorder and is not much lower than major depressive disorder. Nevertheless, PMS/PMDD is still under-recognized in large published epidemiological studies, as well as assessments of burden of disease. It is demonstrated here that the burden of PMS/PMDD as well as the disability adjusted life years (DALY) lost due to this repeated-cyclic disorder is in the same magnitude as major recognized disorders.Appropriate recognition of the disorder and its impact should lead to treatment of more women with PMS/PMDD. Efficacious treatments are available. They should reduce individual suffering and impact on family, society, and economy. (C) 2003 Elsevier Science Ltd. All rights reserved.