Hepatitis C Virus Infection in Persons Who Inject Drugs in the Middle East and North Africa: Intervention Strategies.

Hepatitis C Virus Infection in Persons Who Inject Drugs in the Middle East and North Africa: Intervention Strategies.
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DOI:
10.3390/v13071363
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发表时间:
2021-07-14
期刊:
Viruses
影响因子:
--
通讯作者:
Mathur P
Mathur P
中科院分区:
其他
文献类型:
--
作者:
Khalsa JH;Mathur P

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在中东和北非(MENA)地区,丙型肝炎病毒感染的发病率和患病率很高,无论是否患有药物使用障碍(SUD),但只有少数人接受全面护理。高效的直接作用的抗病毒药物(DAA)可以大大降低成本;然而,只有在综合护理策略针对HCV感染和传播风险最高的人群并改善护理的可及性时,才能实现完全消除丙型肝炎病毒(HCV)。由于中东和北非地区SUD的高患病率,消除HCV的战略必须侧重于跨多个亚专业的综合医疗保健,包括成瘾医学、精神病学、传染病、肝病学和社会工作。在这份邀请稿中,我们回顾了中东和北非地区的HCV流行病学,并强调了实现WHO到2030年根除HCV目标的干预策略。
There is a high incidence and prevalence of hepatitis C viral infection in persons with or without substance use disorders (SUDs) in the Middle East and North Africa (MENA) region, but only a small number receive comprehensive care. Highly effective direct-acting antiviral (DAA) medications are available at substantially lower costs; however, complete elimination of the hepatitis C virus (HCV) can only be achieved if integrated care strategies target those at highest risk for HCV infection and transmission and improve access to care. Due to the high prevalence of SUD in the MENA region, strategies to eliminate HCV must focus on integrated healthcare across multiple subspecialties, including addiction medicine, psychiatry, infectious diseases, hepatology, and social work. In this invited manuscript, we review the epidemiology of HCV in the MENA region and highlight intervention strategies to attain the WHO’s goal of HCV eradication by 2030.
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