OPTIMIZED PARAMETERS FOR A-DNA AND B-DNA
OPTIMIZED PARAMETERS FOR A-DNA AND B-DNA
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DOI：
10.1016/0006-291x(72)90243-4
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发表时间：
1972-01-01
影响因子：
3.1
通讯作者：
HUKINS, DWL
中科院分区：
文献类型：
--
作者：
ARNOTT, S;HUKINS, DWL
给出了 DNA A 和 B 构象的原子坐标和其他立体化学参数。所呈现的分子结构具有通过相关单体的精确 X 射线晶体学分析所定义的键长、键角和呋喃糖环构象的最可能值。构象角具有与从聚合物本身观察到的 X 射线衍射数据提供最佳（最小二乘）拟合的值。 A-和 B-DNA 之间的主要区别在于呋喃糖环的构象，A 为 (C3-endo)，B 为 (C3-exo)。
Atomic coordinates and other stereochemical parameters are presented for the A and B conformations of DNA. The molecular structures presented have the most probable values of bond-lengths, bond-angles and furanose ring conformations as defined by accurate X-ray crystallographic analyses of relevant monomers. Conformation-angles have values that provide the best (least-squares) fit with the X-ray diffraction data observed from the polymers themselves. The major difference between A-and B-DNA is in the conformation of the furanose ring that is (C3-endo) for A and (C3-exo) for B.