Elevated pain thresholds correlate with dissociation and aversive arousal in patients with borderline personality disorder
Elevated pain thresholds correlate with dissociation and aversive arousal in patients with borderline personality disorder
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DOI：
10.1016/j.psychres.2005.04.009
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发表时间：
2007-01-15
影响因子：
11.3
通讯作者：
Schmahl, Christian
中科院分区：
文献类型：
--
作者：
Ludaescher, Petra;Bohus, Martin;Schmahl, Christian
除了减少疼痛感知，边缘型人格障碍（BPD）患者在主观应激条件下显示出比非应激条件下更高的疼痛阈值。然而，到目前为止，尚未研究压力症状和疼痛阈值之间的相关性。使用一种新的和方便的方法，电刺激，我们预计更高的疼痛和检测阈值的BPD患者比健康对照组，以及疼痛阈值和BPD患者的压力症状（厌恶性觉醒和解离）之间的正相关性。12名女性BPD患者和12名健康对照被纳入研究。电刺激施加在右手食指上，通过逐渐加强刺激来评估检测和疼痛阈值。我们发现，与健康对照组相比，BPD患者的疼痛阈值显著升高，但患者和对照组之间的检测阈值没有差异。在患者中，疼痛阈值和分离之间以及疼痛阈值和厌恶性唤醒之间存在显着的正相关。除了证明BPD患者疼痛阈值和应激症状之间的密切相关性外，本研究还重复了BPD患者疼痛感知降低的早期发现。测量电痛阈是一种有效和合理的方法，用于更大的研究。(c)2006爱思唯尔爱尔兰有限公司保留所有权利。
In addition to reduced pain perception, patients with borderline personality disorder (BPD) show higher pain thresholds under subjective stress conditions as compared with non-stress conditions. However, the correlation between symptoms of stress and pain thresholds has not been investigated so far. Using a new and convenient methodology, electric stimulation, we expected higher pain and detection thresholds in patients with BPD than in to healthy controls as well as a positive correlation between pain thresholds and symptoms of stress (aversive arousal and dissociation) in BPD patients. Twelve female patients with BPD and twelve healthy controls were included in the study. Electric stimulation was applied on the right index finger, and detection and pain thresholds were assessed by gradually intensifying the stimuli. We found significantly elevated pain thresholds in patients with BPD as compared with healthy controls, but no difference between patients and controls in detection thresholds. In patients, a significant positive correlation was revealed between pain thresholds and dissociation as well as between pain thresholds and aversive arousal. Besides demonstrating a close correlation between pain thresholds and symptoms of stress in patients with BPD, this study replicated earlier findings of reduced pain perception in patients with BPD. Measuring electric pain thresholds is a valid and reasonable method for larger studies. (c) 2006 Elsevier Ireland Ltd. All rights reserved.