Preparation of Some Multifunctionalized Methylenephosphines by Reactions of Chloro[(2,4,6-tri-t-butylphenyl)phosphinidene]methyllithiums with Carbonyl Compounds
Preparation of Some Multifunctionalized Methylenephosphines by Reactions of Chloro[(2,4,6-tri-t-butylphenyl)phosphinidene]methyllithiums with Carbonyl Compounds
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氯代[(2,4,6-三叔丁基苯基)次膦基]甲基锂与羰基化合物反应制备多官能化亚甲基膦
DOI：
10.1246/bcsj.68.1206
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发表时间：
1995
影响因子：
4
通讯作者：
M. Yasunami
中科院分区：
文献类型：
--
作者：
M. Yoshifuji;S. Ito;Kozo Toyota;M. Yasunami
分别由二氯亚甲基-或(E)-氯亚甲基-膦与丁基锂制备的(Z)-或(E)-氯(次膦亚基)甲基锂试剂与羰基化合物反应得到相应的官能化亚甲基膦。尽管在反应的初始步骤中保留了产物的立体化学，但在某些情况下，所得的亚甲基膦发生了E/Z异构化反应。通过E-锂试剂与异氰酸苯酯反应，首次得到带有P=C键的咪唑烷二酮类化合物； Z-异构体的结构通过X射线分析确定。
Either a (Z)- or (E)-chloro(phosphinidene)methyllithium reagent, prepared from dichloromethylene- or (E)-chloromethylene-phosphine with butyllithium, respectively, reacted with carbonyl compounds to give the corresponding functionalized methylenephosphines. Although the stereochemistry of the products was retained during the initial step of the reaction, in some cases E/Z isomerization reactions occurred to the resulting methylenephosphines. Imidazolidinediones bearing the P=C bond were obtained for the first time by a reaction of the E-lithium reagent with phenyl isocyanate; the structure of the Z-isomer was determined by X-ray analysis.