Is Vitamin D Deficiency a Risk Factor for Respiratory Distress Syndrome?
Is Vitamin D Deficiency a Risk Factor for Respiratory Distress Syndrome?
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DOI：
10.1024/0300-9831/a000165
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发表时间：
2013-08-01
影响因子：
2.3
通讯作者：
Kucukoduk, Sukru
中科院分区：
文献类型：
--
作者：
Ataseven, Fevzi;Aygun, Canan;Kucukoduk, Sukru
背景：已有研究表明胎儿宫内肺发育与维生素D[25(OH)D]有关，但尚无研究探讨维生素D缺乏是否为早产儿呼吸窘迫综合征(RDS)的危险因素。目的：在这项研究中，我们调查了25(OH)D缺乏是否为RDS的危险因素。方法：在父母知情同意的情况下，对152例29~35周出生的早产儿进行研究。在出生后24小时内采集外周血样，用液相色谱-串联质谱仪测定25(OH)D水平。记录婴儿的人口学特征和RDS的诊断。结果：在组早产儿中，25(OH)D水平与重度缺乏症相容(P
Background: Previous studies have shown the relationship between in utero lung development and vitamin D [25(OH)D], but there have been no studies to investigate whether vitamin D deficiency is a risk factor for respiratory distress syndrome (RDS) in preterm babies. Objectives: In this study, we investigated if 25(OH)D deficiency is a risk factor for RDS. Methods: One hundred fifty-two preterm newborns, born at 29-35 weeks gestational age, were included in the study following informed consent from the parents. Peripheral blood samples were collected within the first 24 hours of life and 25(OH)D levels were measured by liquid chromatography-tandem mass spectrometry. Demographic characteristics of the babies and the diagnosis of RDS were recorded. Results: In 64% of preterm infants, 25(OH)D levels were compatible with severe deficiency (